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Effect of pilocarpine mouthwash on salivary flow BJMBR
Bernardi,R.; Perin,C.; Becker,F.L.; Ramos,G.Z.; Gheno,G.Z.; Lopes,L.R.; Pires,M.; Barros,H.M.T..
Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration. Adverse effects are dose-dependent and include sudoresis, facial blushing and increased urinary frequency. The objective of the present study was to evaluate the effects of topical pilocarpine solutions as mouthwashes on salivary flow and their adverse effects on healthy subjects. Forty volunteers received 10 ml 0.5, 1 and 2% pilocarpine solutions or 0.9% saline in a randomized, double-blind, placebo-controlled manner. Salivation was measured before and 45, 60 and 75 min after mouth rinsing for 1 min with 10 ml of saline or pilocarpine solutions. Vital signs were measured and ocular,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pilocarpine; Mouth rinsing; Mouthwash; Xerostomia; Salivation.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100015
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Minor Salivary Glands Morphology in Xerostomia Patients International Journal of Morphology
Liquidato,Bianca Maria; Barros,Mirna Duarte; Filho,Ivo Bussoloti; Pereira,Celina Siqueira Barbosa; Macéa,Maria Inêz Marcondes.
The minor salivary glands are found scattered throughout the oral mucosa, especially in the lips and soft palate mucosa. Several factors can cause xerostomia, whereas the salivary glands histological characteristics are also considered as factors for defining the etiology. Thus, the minor salivary glands biopsy represents an essential tool for attending the required diagnosis criterion in the classification of Sjögren's Syndrome patients, since it does not present risk for the patient. The objective of this study is to determine the histological description of the minor salivary glands obtained from the biopsies of xerostomia patients and to classify the minor salivary gland histological aspect as the Sjögren's Syndrome. Forty laminas of xerostomia...
Tipo: Journal article Palavras-chave: Sjögren's syndrome; Xerostomia; Salivary glands; Saliva; Diagnosis.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400031
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